Procedure · Knee · Non-surgical

Arthrosamid® Injections

A single injection of polyacrylamide hydrogel into the knee joint, offering a non-surgical option for knee osteoarthritis pain when first-line treatments aren't giving enough relief.

In clinic time~15 minutes
AnaestheticLocal only
DowntimeMinimal
TypeNon-surgical

What it is

Arthrosamid is a polyacrylamide hydrogel injected directly into the knee joint. Unlike steroid or standard hyaluronic acid injections, which are typically absorbed by the body over weeks, it integrates into the joint's soft tissue lining and is intended to provide longer-lasting cushioning and support for an osteoarthritic knee.

Who it's for

It's generally considered for patients with knee osteoarthritis whose pain is affecting daily life but who are not yet ready for knee replacement surgery, or are not suitable candidates for it, and for whom simpler measures such as physiotherapy, weight management, activity modification and standard pain relief haven't given enough benefit. It can also be a useful option for patients who want to delay surgery, or who have medical reasons that make surgery higher risk.

The procedure

The injection is given in clinic under local anaesthetic, usually guided by ultrasound to ensure accurate placement within the joint. It typically takes around fifteen minutes, with no incision and no need for a general anaesthetic or hospital stay.

What to expect afterwards

  • Most patients can return to normal daily activity within a day or two.
  • Some mild swelling or discomfort at the injection site is common in the first few days.
  • Benefit tends to build gradually over the following weeks rather than appearing immediately.
  • It does not reverse existing joint damage, and does not rule out knee replacement being needed at a later stage.

Risks & considerations

As with any joint injection, there's a small risk of infection, joint reaction or discomfort at the injection site. Whether it is an appropriate option, and how it fits alongside other treatments, is best assessed based on the severity and pattern of your knee osteoarthritis at consultation.

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